R.V. Paul Chan, MD, MSc, FACS

The John H. Panton Professor of Ophthalmology
Vice Chair for Global Ophthalmology
Director, Pediatric Retina and Retinopathy of Prematurity Service
Co-Director, Vitreoretinal Fellowship Program
Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago

Education

Medical School—Temple University School of Medicine
Residency—New York-Presbyterian Hospital, Weill Cornell Medical College
Fellowship in Vitreoretinal Surgery—Massachusetts Eye and Ear Infirmary, Harvard Medical School

Research Interests

Global ophthalmology
Telemedicine and tele-education
New methods of diagnosing and managing pediatric retinal disease

See a representative list of Dr. Chan’s journal articles in PubMed.

Recent Publications

Yonekawa Y, Wu WC, Nitulescu CE, Chan RVP, Thanos A, Thomas BJ, Todorich B, Drenser KA, Trese MT, Capone A Jr. Progressive retinal detachment in infants with retinopathy of prematurity treated with intravitreal bevacizumab or ranibizumab. Retina. 2018 Jun;38(6):1079-1083.

Wang B, Toslak D, Alam MN, Chan RVP, Yao X. Contact-free trans-pars-planar illumination enables snapshot fundus camera for nonmydriatic wide field photography. Sci Rep. 2018 Jun 8;8(1):8768.

Toslak D, Thapa D, Chen Y, Erol MK, Paul Chan RV, Yao X. Wide-field fundus imaging with trans-palpebral illumination. Proc SPIE Int Soc Opt Eng. 2017 Jan 28;10045. pii: 100451X.

Swan R, Kim SJ, Campbell JP, Paul Chan RV, Sonmez K, Taylor KD, Li X, Chen YI, Rotter JI, Simmons C, Chiang MF; Imaging and Informatics in ROP Research Consortium. The genetics of retinopathy of prematurity: a model for neovascular retinal disease. Ophthalmol Retina. 2018 Sep;2(9):949-962.

Shah N, Gupta MP, Chan RVP. Persistent Angiographic Abnormalities After Intravitreal Anti-Vascular Endothelial Growth Factor Therapy for Retinopathy of Prematurity. JAMA Ophthalmol. 2018 Apr 1;136(4):436-437.

Rothschild MI, Russ R, Brennan KA, Williams CJ, Berrones D, Patel B, Martinez-Castellanos MA, Fernandes A, Hubbard GB 3rd, Chan RVP, Yang Z, Olsen TW. The Economic Model of Retinopathy of Prematurity (EcROP) Screening and Treatment: Mexico and the United States. Am J Ophthalmol. 2016 Aug;168:110-121.

Peng Tian, Ataer-Cansizoglu E, Kalpathy-Cramer J, Ostmo S, Jonas K, Chan RV, Campbell JP, Chiang MF, Erdogmus D. Toward a severity index for ROP: An unsupervised approach. Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:1312-1315.

Patel SN, Martinez-Castellanos MA, Berrones-Medina D, Swan R, Ryan MC, Jonas KE, Ostmo S, Campbell JP, Chiang MF, Chan RVP; GEN-ROP; i-ROP Research Consortium. Assessment of a Tele-education System to Enhance Retinopathy of Prematurity Training by International Ophthalmologists-in-Training in Mexico. Ophthalmology. 2017 Jul;124(7):953-961.

Patel SN, Klufas MA, Douglas CE, Jonas KE, Ostmo S, Berrocal A, Capone A Jr, Martinez-Castellanos MA, Chau F, Drenser K, Ferrone P, Orlin A, Tsui I, Wu WC, Gupta MP, Chiang MF, Chan RV; i-ROP Research Consortium. Influence of Computer-Generated Mosaic Photographs on Retinopathy of Prematurity Diagnosis and Management. JAMA Ophthalmol. 2016 Nov 1;134(11):1283-1289.

Moleta C, Campbell JP, Kalpathy-Cramer J, Chan RVP, Ostmo S, Jonas K, Chiang MF; Imaging & Informatics in ROP Research Consortium. Plus Disease in Retinopathy of Prematurity: Diagnostic Trends in 2016 Versus 2007. Am J Ophthalmol. 2017 Apr;176:70-76.

Marlow E, Chan RVP, Oltra E, Rusu I, Gupta MP. Retinal Avascularity and Neovascularization Associated With LAMA1 (laminin1) Mutation in Poretti-Boltshauser Syndrome. JAMA Ophthalmol. 2018 Jan 1;136(1):96-97.

Lam WC, Chan RVP. Pediatric Retinal Diseases. Asia Pac J Ophthalmol (Phila). 2018 May-Jun;7(3):129.

Kim SJ, Port AD, Swan R, Campbell JP, Chan RVP, Chiang MF. Retinopathy of prematurity: a review of risk factors and their clinical significance. Surv Ophthalmol. 2018 Sep - Oct;63(5):618-637.

Kim SJ, Campbell JP, Ostmo S, Jonas KE, Chan RVP, Chiang MF; Imaging and Informatics in Retinopathy of Prematurity (i-ROP) Research Consortium. Changes in Relative Position of Choroidal Versus Retinal Vessels in Preterm Infants. Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6334-6341.

Kim SJ, Campbell JP, Kalpathy-Cramer J, Ostmo S, Jonas KE, Choi D, Chan RVP, Chiang MF; Imaging and Informatics in Retinopathy of Prematurity (i-ROP) Research Consortium. Accuracy and Reliability of Eye-Based vs Quadrant-Based Diagnosis of Plus Disease in Retinopathy of Prematurity. JAMA Ophthalmol. 2018 Jun 1;136(6):648-655.

Kalpathy-Cramer J, Campbell JP, Erdogmus D, Tian P, Kedarisetti D, Moleta C, Reynolds JD, Hutcheson K, Shapiro MJ, Repka MX, Ferrone P, Drenser K, Horowitz J, Sonmez K, Swan R, Ostmo S, Jonas KE, Chan RV, Chiang MF; Imaging and Informatics in Retinopathy of Prematurity Research Consortium. Plus Disease in Retinopathy of Prematurity: Improving Diagnosis by Ranking Disease Severity and Using Quantitative Image Analysis. Ophthalmology. 2016 Nov;123(11):2345-2351.

Gupta MP, Patel S, Orlin A, Marlow E, Chee RI, Nadelmann J, Chan RVP, DʼAmico DJ, Kiss S. Spectral domain optical coherence tomography findings in macula-involving cytomegalovirus retinitis. Retina. 2018 May;38(5):1000-1010.

Gupta MP, Dow E, Jeng-Miller KW, Mukai S, Orlin A, Xu K, Yonekawa Y, Chan RVP. Spectral domain optical coherence tomography findings in Coats disease. Retina. 2018 Mar 8.

Ghergherehchi L, Kim SJ, Campbell JP, Ostmo S, Chan RVP, Chiang MF. Plus Disease in Retinopathy of Prematurity: More Than Meets the ICROP? Asia Pac J Ophthalmol (Phila). 2018 May-Jun;7(3):152-155.

Darwish D, Chee RI, Patel SN, Jonas K, Ostmo S, Campbell JP, Chiang MF, Chan RVP. Anti-Vascular Endothelial Growth Factor and the Evolving Management Paradigm for Retinopathy of Prematurity. Asia Pac J Ophthalmol (Phila). 2018 May-Jun;7(3):136-144.

Chuluunbat T, Chan RV, Wang NK, Lien R, Chen YP, Chao AN, Chen KJ, Chen TL, Hwang YS, Lai CC, Wu WC. Nonresponse and Recurrence of Retinopathy of Prematurity After Intravitreal Ranibizumab Treatment. Ophthalmic Surg Lasers Imaging Retina. 2016 Dec 1;47(12):1095-1105.

Chee RI, Chan RVP. Universal newborn eye screening: an effective strategy to improve ocular health? Eye (Lond). 2018 Jan;32(1):50-52.

Chang A, Schlottmann PG, Chan RVP. Latest Developments in the Management of AMD. Asia Pac J Ophthalmol (Phila). 2017 Nov-Dec;6(6):477-478.

Chan RVP. 8 Questions with Darius Moshfeghi. Ophthalmic Surg Lasers Imaging Retina. 2017 Oct 1;48(10):870-872.

Campbell JP, Ryan MC, Lore E, Tian P, Ostmo S, Jonas K, Chan RVP, Chiang MF; Imaging & Informatics in Retinopathy of Prematurity Research Consortium. Diagnostic Discrepancies in Retinopathy of Prematurity Classification. Ophthalmology. 2016 Aug;123(8):1795-1801.

Campbell JP, Ryan MC, Chan RVP, Chiang MF. Reply. Ophthalmology. 2017 May;124(5):e46-e47.

Campbell JP, Nudleman E, Yang J, Tan O, Chan RVP, Chiang MF, Huang D, Liu G. Handheld Optical Coherence Tomography Angiography and Ultra-Wide-Field Optical Coherence Tomography in Retinopathy of Prematurity. JAMA Ophthalmol. 2017 Sep 1;135(9):977-981.

Campbell JP, Kalpathy-Cramer J, Erdogmus D, Tian P, Kedarisetti D, Moleta C, Reynolds JD, Hutcheson K, Shapiro MJ, Repka MX, Ferrone P, Drenser K, Horowitz J, Sonmez K, Swan R, Ostmo S, Jonas KE, Chan RV, Chiang MF; Imaging and Informatics in Retinopathy of Prematurity Research Consortium. Plus Disease in Retinopathy of Prematurity: A Continuous Spectrum of Vascular Abnormality as a Basis of Diagnostic Variability. Ophthalmology. 2016 Nov;123(11):2338-2344.

Burke MJ, Chan RVP, Friedman IB, Suh DW, Wagner RS. Immediate Preoperative and Postoperative Management for Strabismus Surgery. J Pediatr Ophthalmol Strabismus. 2018 Mar 1;55(2):77-79.

Biten H, Redd TK, Moleta C, Campbell JP, Ostmo S, Jonas K, Chan RVP, Chiang MF; Imaging & Informatics in Retinopathy of Prematurity (ROP) Research Consortium. Diagnostic Accuracy of Ophthalmoscopy vs Telemedicine in Examinations for Retinopathy of Prematurity. JAMA Ophthalmol. 2018 May 1;136(5):498-504.

Berenberg TL, Van Tassel SH, Patel SN, Chan RV. Juvenile X-Linked Retinoschisis: A Comparison of Imaging Modalities and Review of Angiographic Findings. Retina. 2016 Dec;36(12):e117-e119.