Mark I Rosenblatt MD, PhD, MBA

Professor and Head of the Department of Ophthalmology & Visual Sciences
Illinois Lions/Charles I. Young Chair in Ocular Research
Director of Corneal Regenerative Medicine Laboratory
Associate Director, Medical Science Training Program (MSTP)

Education

BS cum laude—University of Miami Honors Program in Medical Education
MD—University of Miami School of Medicine Combined MD/PhD Program, elected to Alpha Omega Alpha
PhD in Biochemistry, Cell, and Molecular Biology—University of Miami School of Medicine Combined MD/PhD
MBA—New York University Stern School of Business
Residency—Massachusetts Eye and Ear Infirmary, Harvard Medical School
Research Fellowship—Schepens Eye Research Institute, Harvard Medical School
Clinical Fellowship in Cornea and External Disease—Massachusetts Eye and Ear Infirmary

Selected Academic Service

Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago
Clinical Operations Committee, Chair
Clinical Finance Committee, Chair
Service Directors Committee, Chair
Cornea Fellowship Selection Committee, Member
Ophthalmology Resident Selection Committee, Member
Resident Education Committee, Member

University of Illinois at Chicago
Medical Science Training Program (MSTP), Associate Director
Ophthalmic Research in Bioengineering, Innovation, and Technology Lab (ORBITLab), Co-Director
University of Illinois / Discovery Partners Institute Clinical Health and Wellness Working Group, Chair
Lung Biology and Pathophysiology Training Program (NIH T32 Grant), Faculty Member
Associate Vice Chancellor for Medical Advancement Search Committee, Member

National and International
Grants Review Committee, Member, Research to Prevent Blindness
Board of Directors, Member, Illinois Society for the Prevention of Blindness
Cultivated Autologous Limbal Epithelial Cells, Data and Safety Monitoring Committee, Member National Eye Institute/Jaeb Center for Health Research
NEI Special Emphasis Panel, Study Section Member Center for Scientific Review/National Eye Institute
International Dry Eye WorkShop (DEWS), Neurobiology Sub-committee, Member
Tear Film and Ocular Surface Society
NEI Review of Clinical Research Grants, Study Section Member, Center for Scientific Review/National Eye Institute
Planning Committee – New Technology, Member, World Ophthalmology Congress, Guadalajara, Mexico

Research Interests

Ocular regenerative medicine
Corneal stem cells
Corneal nerve regeneration
Angiogenesis
Tissue engineering
Biomaterials
Nanomedicine

Recent Publications

  1. Zhong W, Montana M, Santosa SM, Isjwara ID, Huang YH, Han KY, O'Neil C, Wang A, Cortina MS, de la Cruz J, Zhou Q, Rosenblatt MI, Chang JH, Azar DT. Angiogenesis and lymphangiogenesis in corneal transplantation-A review. Surv Ophthalmol. 2018 Jul - Aug;63(4):453-479.
  2. Zhong W, Gao X, Wang S, Han K, Ema M, Adams S, Adams RH, Rosenblatt MI, Chang JH, Azar DT. Prox1-GFP/Flt1-DsRed transgenic mice: an animal model for simultaneous live imaging of angiogenesis and lymphangiogenesis. Angiogenesis. 2017 Nov;20(4):581-598.
  3. Zhang M, Zhou Q, Luo Y, Nguyen T, Rosenblatt MI, Guaiquil VH. Semaphorin3A induces nerve regeneration in the adult cornea-a switch from its repulsive role in development. PLoS One. 2018 Jan 25;13(1):e0191962
  4. Sartaj R, Zhang C, Wan P, Pasha Z, Guaiquil V, Liu A, Liu J, Luo Y, Fuchs E, Rosenblatt MI. Characterization of slow cycling corneal limbal epithelial cells identifies putative stem cell markers. Sci Rep. 2017 Jun 19;7(1):3793.
  5. artaj R, Zhang C, Wan P, Pasha Z, Guaiquil V, Liu A, Liu J, Luo Y, Fuchs E, Rosenblatt MI. Author Correction: Characterization of slow cycling corneal limbal epithelial cells identifies putative stem cell markers. Sci Rep. 2018 Feb 1;8(1):2483.
  6. Rosenblatt MI. Remote Quantitative Sensory Testing and Neuropathic Ocular Pain. JAMA Ophthalmol. 2016 Nov 1;134(11):1298.
  7. Rosenblatt MI. Anti-Infective and Anti-Inflammatory Pharmacotherapies. Handb Exp Pharmacol. 2017;242:119-135.
  8. Lee WB, Kaufman SC, Deng SX, Shtein RM, Rosenblatt MI. Reply. Ophthalmology. 2016 Jul;123(7):e42-3.
  9. Kang KB, Lawrence BD, Gao XR, Luo Y, Zhou Q, Liu A, Guaiquil VH, Rosenblatt MI. Micro- and Nanoscale Topographies on Silk Regulate Gene Expression of Human Corneal Epithelial Cells. Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6388-6398.
  10. Hirata H, Mizerska K, Dallacasagrande V, Rosenblatt MI. Estimating the Osmolarities of Tears During Evaporation Through the "Eyes" of the Corneal Nerves. Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):168-178.
  11. Hirata H, Mizerska K, Dallacasagrande V, Guaiquil VH, Rosenblatt MI. Acute corneal epithelial debridement unmasks the corneal stromal nerve responses to ocular stimulation in rats: implications for abnormal sensations of the eye. J Neurophysiol. 2017 May 1;117(5):1935-1947
  12. Ghezzi CE, Wang L, Behlau I, Rnjak-Kovacina J, Wang S, Goldstein MH, Liu J, Marchant JK, Rosenblatt MI, Kaplan DL. Degradation of silk films in multipocket corneal stromal rabbit models. J Appl Biomater Funct Mater. 2016 Jul 26;14(3):e266-76.
  13. Eslani M, Putra I, Shen X, Hamouie J, Afsharkhamseh N, Besharat S, Rosenblatt MI, Dana R, Hematti P, Djalilian AR. Corneal Mesenchymal Stromal Cells Are Directly Antiangiogenic via PEDF and sFLT-1. Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5507-5517.
  14. Belmonte C, Nichols JJ, Cox SM, Brock JA, Begley CG, Bereiter DA, Dartt DA, Galor A, Hamrah P, Ivanusic JJ, Jacobs DS, McNamara NA, Rosenblatt MI, Stapleton F, Wolffsohn JS. TFOS DEWS II pain and sensation report. Ocul Surf. 2017 Jul;15(3):404-437.
  15. Abdel-Naby W, Cole B, Liu A, Liu J, Wan P, Schreiner R, Infanger DW, Paulson NB, Lawrence BD, Rosenblatt MI. Treatment with solubilized Silk-Derived Protein (SDP) enhances rabbit corneal epithelial wound healing. PLoS One. 2017 Nov 20;12(11):e0188154.
  16. Abdel-Naby W, Cole B, Liu A, Liu J, Wan P, Guaiquil VH, Schreiner R, Infanger D, Lawrence BD, Rosenblatt MI. Silk-Derived Protein Enhances Corneal Epithelial Migration, Adhesion, and Proliferation. Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1425-1433.